Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world's leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world's deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.

A laboratory in the Human Biology Division at Fred Hutchinson Cancer Center is seeking a Pre-Doctoral Research Associate I to work with an interactive collaborative team of scientists investigating the mechanisms of HIV-1 latency and HIV replication using CRISPR screens and validation in T cell and primary cell models.The applicant should be well organized, pay close attention to detail, be reliable and motivated to participate in multiple levels of lab activity.

The Emerman lab has developed a novel screening technology called HIV-CRISPR technology to comprehensively discover the pathways of HIV latency maintenance and HIV replication. This Pre-Doctoral Research Associate I position will further explore hits from existing and new screens further explore the roles of host proteins in HIV biology in T cells.

Responsibilities

The incumbent will perform standard routine and investigative laboratory work in support of scientific research specific to HIV replication and HIV latency using results from recent CRISPR screens as well as new screens.

Major Duties

• Preform experiments at the bench level to support investigative work, potentially including, but not limited to molecular biology, viral infections and assays, DNA sequencing, PCR amplification, RT-PCR amplification, TC culture, BLS2/3 work, including making virus stocks and performing viral infection.
• CRISPR/Cas9 screening and editing, and analysis of results.
• Experiments with primary T cells
• Recover, compile and verify accuracy of research data
• Operate analytical instruments.
• Perform and modify documented protocols and assays
• Maintain laboratory records and compile data on experiments and assays
• Interpret and report on experimental results.
• Present data at local and national meetings
• Prepare manuscripts describing the data and their meaning to the field.

Qualifications

MINIMUM QUALIFICATIONS:

• BA/BS required in a scientific field
• Recent graduate work in related field
• Experience with molecular biology and biochemical method as well as HIV biology.
• A strong interest in research in the area of HIV biology and HIV latency, infectious diseases and global health.
• Evidence of productivity appropriate to a Predoc Res Assc I as measured by publications and presentations, abstracts and posters at conferences.
• Well-organized with strong attention to detail.
• Ability to work independently and perform experiments without day-to-day supervision will be required after training.
• Ability to work as part of a team and to participate in multiple projects in collaboration with different lab members and collaborations with outside labs.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

The annual base salary range for this position is from $41,538 to $100,000, and pay offered will be based on experience and qualifications. Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months).

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