Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world's leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world's deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.

The Clurman Lab (https://research.fredhutch.org/clurman/en.html; TST and Human Biology Divisions) works at the intersection of two fields: cell cycle control and the ubiquitin system. While our work focuses on both tumorigenesis and fundamental regulatory mechanisms in normal biology. Our overall goal is to apply new mechanistic insights to understand cancer development and develop new therapeutic strategies.

Responsibilities

We are seeking a highly qualified and motivated Postdoctoral Fellow to study the molecular control of the cell cycle in both normal and neoplastic contexts. This work will focus on cyclin E-CDK2 activity and regulation in cancer and in normal cells. This includes studies of new substrates, understanding how cyclin E activity and regulatory mechanisms may be therapeutically leveraged, and how cyclin E promotes tumorigenesis. One area of current focus includes studies of head and neck squamous cell cancer. This work will encompass a broad array of approaches, including cell and molecular biology, gene targeting in mice and human cells, and large-scale genomics and proteomics. We value lab members who are highly collaborative but can also independently develop and guide research projects.

Qualifications

• PhD, M.D., or M.D., Ph. D (or equivalent degree) in cell and molecular biology, cancer biology, biochemistry, or a related field.
• Broad expertise in cell and molecular biology methods and the ability to master new techniques and approaches.
• Experience with genetically engineered mouse models of cancer is preferred.
• Excellent written and communication skills.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

The annual base salary range for this position is from $77,976 to $150,000 and pay offered will be based on experience and qualifications.

This position may be eligible for relocation assistance. Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, income-based child care subsidy, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (13 days per year), and paid parental leave (up to 4 weeks).

Our Commitment to Diversity